“ú–{ˆã‰È‘åŠwˆãŠw‰ïŽGŽ Online Journal ƒƒCƒ“ƒiƒrƒQ[ƒVƒ‡ƒ“‚ð”ò‚΂·
‘–ÚŽŸ > †–ÚŽŸ > Abstract ƒz[ƒ€‚Ö–ß‚é
Abstract

‘æ3Šª 2007”N2ŒŽ@‘æ1†

‘S•¶PDF (440K)

¡Ç—á•ñ

‘½”­«”X–Et‚ɍ‡•¹‚µ‚½‹}«‘å“®–¬‰ð—£‚Ì3—á
’†‘º@—LŠó1, Žl‘q@Š°Žq1, ‰Á“¡@‰ë•F1, ’†“c@~2, “c’†@Œ[Ž¡2, —с@GŒõ3
1“ú–{ˆã‰È‘åŠw6”N¶
2“ú–{ˆã‰È‘åŠw•t‘®•a‰@W’†Ž¡—ÃŽº
3“ú–{ˆã‰È‘åŠw•t‘®•a‰@•úŽËü‰È

Acute Aortic Dissection Associated with Adult Autosomal Dominant Polycystic Kidney Disease: Three Case Reports and a Review
Yuki Nakamura1, Hiroko Yotsukura1, Masahiko Kato1, Jun Nakat2, Keiji Tanaka2 and Hiromitsu Hayashi3
1Sixth-year Medical Student, Nippon Medical School
2Division of Intensive and Coronary Care Unit, Nippon Medical School Hospital
3Department of Radiology, Nippon Medical School Hospital

Adult autosomal dominant polycystic kidney disease (ADPKD) is a common hereditary disorder responsible for 8% to 10% of cases of end-stage chronic renal failure. The extrarenal complications of ADPKD kidney include cardiovascular disorders (such as mitral valve prolapse syndrome, bicuspid aortic valve, aortic coarctation, aortic aneurysm, and aortic dissection), intracranial aneurysms, diverticulum of colon, hepatic cysts, inguinal hernia, and urinary calculus. Acute aortic dissection (AAD) associated with ADPKD is life-threatening. There are few reports of ADPKD with AAD. To the best of our knowledge, only 9 cases have been found, including at autopsy, in Japan. We have treated 121 patients with AAD in the last 5 years, and 3 of these 121 patients also had ADPKD in the intensive care unit of Nippon Medical School. We report clinical features of cases of ADPKD with AAD on the basis of 12 cases, including 9 previously reported cases and our 3 cases. AAD requires urgent antihypertensive therapy, which often aggravates renal function. Priority should be given to antihypertensive therapy in emergent cases. In fact, 2 of our patients required hemodialysis owing to antihypertensive therapy for AAD. Close cooperation between cardiologists and nephrologists is essential.

“úˆã‘åˆã‰ïŽ 2007; 3(1), 25-29

Key words
adult autosomal dominant polycystic kidney disease, acute aortic dissection, hemodialysis

Correspondence to
Keiji Tanaka, MD, PhD, FJCC, Division of Intensive and Coronary Care Unit, Nippon Medical School Hospital, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan
E-mailFk-tanaka@nms.ac.jp

Žó•tF2006”N8ŒŽ22“ú@Žó—F2006”N11ŒŽ21“ú

ƒƒCƒ“ƒiƒrƒQ[ƒVƒ‡ƒ“‚Ö–ß‚é ‚±‚̃y[ƒW‚̃gƒbƒv‚Ö–ß‚é