Significant Cerebral Atherosclerosis in an Elderly Patient with Metabolic Syndrome
Department of Internal Medicine (Divisions of Cardiology, Hepatology, Geriatrics, and Integrated Medicine)
A 65-year-old man was referred to our hospital due to the recurrence of transient ischemic attacks (TIA). He has severe atherosclerosis of the cerebral arteries associated with metabolic syndrome and dyslipidemia. After substitution of a standard diet and combination drug therapy, such as anti-hypertensive drugs, stain, aspirin, and cilostasole, all laboratory findings improved. The patient did not present any symptoms of central nerve system after he was discharged. At 70 years he was diagnosed of angina pectoris and treated by nicorandil. Cognitive and psychiatric decline was observed from 71 years old. We diagnosed frontotemporal dementia on the basis of clinical feature and MRI findings at 72 years old.
日医大医会誌 2008; 4(3), 153-156
atherosclerosis, metabolic syndrome, insulin resistance, frontotemporal dementia
Hiroshi Nakano, Department of Internal Medicine, Division of Geriatrics, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan